Takemura Laboratory


Research

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The 21st century is often regarded as the age of bioscience. It is widely presumed that our lives are going to be overwhelmed with biotechnology products including genetically modified foods, and that genetic diagnosis and gene therapy are going to be commonly available in the near future.

(1)Biology Education: Takemura Laboratory is engaged in the improvement of bioscience and biology education at the level of secondary education to meet the needs of these times, especially with respect to the research and development of new biology teaching materials and laboratory experiments for students emphasizing the study of molecular biology and evolutionary biology.

(2)Giant Virus Biology: Moreover, studies have been conducted at Takemura Laboratory to elucidate eukaryote evolution and its processes via basic research on “Giant viruses,” which mainly infect eukaryotic microorganisms.

Takemura Laboratory aims to train junior high school science teachers, high school biology teachers, and others to adopt a global view based on both “educational research” and “basic research.”

[Major research themes]
(1) Research and development of original biology teaching materials and laboratory experiments for students being useful in secondary education (junior high schools and high schools).
(2) Genomic, Biochemical, and Morphological studies of ”Giant viruses”.

Dr. Masaharu Takemura
Professor (PI)

[Main achievements of Dr. Takemura]

Takemura M et al. (2015) Evolution of eukaryotic DNA polymerases via interaction between cells and large DNA viruses. J. Mol. Evol. 81, 24-33. (A paper proposing a possible link between giant virus evolution and the eukaryotic evolution)
Takemura M & Kurabayashi M. (2014) Using analogy role-play activity in an undergraduate biology classroom to show central dogma revision. Biochem. Mol. Biol. Edu. 42, 351-356. (A paper describing new role-play activity for learning central dogma)
Takemura M. (2001) Poxviruses and the origin of the eukaryotic nucleus. J. Mol. Evol. 52, 419-425. (The first paper proposing a possible link between the DNA viruses and the origin of the eukaryotic nucleus)
Takemura M et al. (1997) Phosphorylated retinoblastoma protein stimulates DNA polymerase alpha. Oncogene 15, 2483-2492. (The first paper proposing positive function of the hyper-phosphorylated retinoblastoma (Rb) protein)